Steven and his colleagues investigated the molecular and cellular characteristics of maternal cells (short: MMc) that are transferred to the fetus during pregnancy. We showed that MMc seed the developing brain and influence the oscillatory entrainment of prefrontal-hippocampal circuits by altering microglia-induced synapse elimination. By this pathway, maternal cells contribute to the development of behavioral abilities in neonatal and pre-juvenile offspring.
in the developing brain (E18.5) of a non-expressing offspring.
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